Glutatione and ATP

Glutathione and ATP

As I wrote earlier I follow a protocol to increase my glutathione levels

Before I started I had blood tests done:

Glutathione:      3.20 mmol/l                               range: 3.1 - 5.9 mmol/l
ATP:                 0.46 nmol /1 million cells          range: 0.38 - 0.99 nmol/1million cells

Then I took S-Acetylglutathione for 4 weeks (and 3 days) at 800 mg/day

Then I tested again after 6 weeks:

Glutathione:      5.30
ATP:                 0.50

the increase in Glutathione is quite spectacular, the one in ATP not so much but it still is an increase. At this moment in time, even though the glutathione levels have improved I do not feel much better, just a tiny little bit which corresponds to the mini improvement in ATP. I did have a few better days but now I am flat on my back again. So, maybe it just takes longer for the new glutathione levels to positively influence ATP production or, maybe there is a different cause for my impaired mitochondrial function. I'll keep researching.

For the time being I will continue taking the Acetylglutathione but only 400mg/day and test again in 4-6 weeks. Ideally I would like to have a level of 5.80 which is what Dr.Gesswein advises.

His initial protocoll for CFS is:
(but he stresses that regular testing is imperative to adjust/reduce the doses as necessary to arrive at the ideal levels and not overmedicate)

S- Acetylglutathione         800 - 1200 mg          ideal levels:  5.80 mmol/l
B12 (Methylcobalamine) 10.000 mcg                                     min. 0.8 mcg/l
D3*                                   20.000 IU*                                     180-230 ng/l*
Vitamin C                         2-3 gr                                
Vitamin A                         10.000 IU                                       1.5 mcg/ml
Zinc                                   50 mg                                             15
Magnesium                       500 mg
Calcium                            500-1000 mg
Quercitine                         1000 mg
Amino acid complex         18,250 mg

* Gesswein'.s opinion regarding D3 is very different from others and his ideal levels might well be too high. Check out Dr. Gominak at http://drgominak.com/lecture , she says ideal levels are 60-80.


(Disclaimer: I am not a doctor. I am only searching for solutions and trying out things to improve my quality of life. Do not try anything I did. Always ask a qualified doctor for advice before trying something. All I am writing about are my personal experiences as my very own guinea pig. Everybody is different and I cannot be held responsible for anything anybody tries out.)